Place it as the first reaction in a quick sequence, then follow with a damn meme sound button for the payoff and a Ceeday huh sound button if the scene keeps escalating through the next cut in your edit.
About this sound
This is a short 1.5-second voice clip of someone blurting out 'what the fuck' in a flat, stunned tone. It gives a listener that instant mix of confusion, disbelief and dry amusement you feel when something makes no sense, lands wrong, or catches you completely off guard in the middle of a normal moment.