Place it just after the odd line or reaction in your edit, then follow it with the Bruh sound for a second beat, or open with the Emotional Damage sound and use this clip as the follow-up.
About this sound
This 12-second clip is built around the short, repeated skeu skeu vocal phrase that gives the meme its name. It feels silly and slightly awkward, like a joke that hangs in the air a beat too long. It comes from a TikTok reference that spread as a meme sound.