Place it at the end of a reversed joke or failed explanation, then follow it with the Bruh sound for a reaction, or open with Goofy Ahh Sounds before it for a build-up.
About this sound
This 1.4-second clip plays the words sour cream in reverse, turning a familiar phrase into a strange, garbled burst of speech that sounds almost like another language. It feels funny and oddly unsettling, the kind of sound that makes listeners pause and replay it to work out what they just heard. It comes from Inanimate Insanity.