The line is from Portal 2, Valve's 2011 puzzle game, where the chapter itself is titled The Part Where He Kills You. GLaDOS says it as Wheatley, voiced by Stephen Merchant, seizes control and tries to kill Chell near the finale. The chapter title also became an achievement name, helping the quote stick in gaming culture. Players clipped the delivery for edits and streams, and it spread as a shorthand warning for any obvious ambush, scripted betrayal, or moment where a friendly guide stops being friendly.