Place it right at the end of a setup clip, immediately after the bad idea is shown, then follow it with the Bruh sound to underline the disbelief. That two-beat ending keeps the joke focused and gives the reaction a clear place to land.
About this sound
This is a very short spoken clip of Donald Trump saying 'can't let that happen' in a firm, clipped delivery that lasts just over a second. The line lands as a blunt refusal, giving listeners a quick sense of authority and finality that feels both serious and funny out of context. It works best as a sharp veto, cutting off a suggestion before it can go any further.