Place it near the end of a roast segment, after a boast or challenge clip and before a crowd laugh or record scratch, so it closes the exchange. Follow it with a reaction shot, then a second roast clip to keep the back-and-forth going.
About this sound
This 38-second Spanish clip uses a stiff synthetic Loquendo-style voice to deliver the line 'tu madre tiene el Empire State.' The flat computer narration makes the nonsense insult feel dryly funny and strangely confident, turning a familiar your-mom setup into a surreal punchline. It grew out of Spanish-speaking Loquendo meme culture, spreading through reposts, meme pages and WhatsApp forwards rather than from a film or television source.