This sound is associated with Murder Drones, the animated sci-fi web series by GLITCH Productions, and specifically with Episode 7. Fans clipped the moment of Uzi and N screaming and reused it in short-form edits, reaction posts, and fandom memes. Its popularity comes from how quickly it communicates alarm while still sounding distinctly tied to the show's tone and characters. Even outside the fandom, creators use it when they want a compact two-character panic reaction instead of a generic scream.