Half-Life 2 was released by Valve in 2004 and its short NPC voice lines have been reused by players for years in machinima, mods and meme edits. The scientist characters speak in a distinctive earnest style carried over from the series, which makes even a single word recognisable to fans. As soundboards and short video edits grew, isolated lines like this yes were clipped on their own so they could be dropped into unrelated scenes, where the contrast between the serious tone and a silly prompt keeps the joke working.