Nani is the Japanese word for what, and this short shout became a staple of anime reaction memes online. Short clips of stunned characters exclaiming it spread through YouTube, TikTok and Discord edits, where it was used to punctuate reveals, roasts and unbelievable moments. Its appeal is its simplicity: even viewers who do not speak Japanese instantly understand the shock it conveys. That universal readability has kept it in regular rotation for meme editors, streamers and reaction creators long after its first viral wave.