William Birkin is the Umbrella scientist behind the G-Virus in Resident Evil 2, and the line returns in Capcom's 2019 remake of the game. Obsessed with his research and threatened by attempts to seize it, he treats the virus as a personal creation rather than a weapon. Clips of the shout later circulated among Resident Evil fans as a reaction sound, used whenever someone becomes fiercely protective of a build, edit, drawing or idea they made themselves and refuses to hand it over.