Pus valio verga comes from everyday Mexican Spanish slang, where pues is shortened to pus and valio verga is a vulgar way of saying something is ruined beyond saving. Short voice notes using the phrase circulated in Spanish speaking chats and edits long before soundboards picked it up, because the line works without any context. It spread as a ready made reaction for fails, defeats and plans gone wrong, and it remains popular in Latin meme videos where a single resigned line can close a joke better than an explanation.