The Sanctuary Guardian theme comes from EarthBound, the 1995 Super Nintendo RPG known in Japan as Mother 2. It scores the boss fight deep in the Stonehenge base, where the party battles a bizarre alien guardian. The track's warped, nightmarish arrangement became famous online through retro gaming compilations and creepypasta-style videos, where it soundtracked cursed edits and unsettling compilations. Meme creators later adopted it as shorthand for anything deeply wrong or unhinged, keeping one of the SNES era's strangest compositions alive in modern meme culture.