The clip circulates online as a short reaction taken from comedian and podcast host Andrew Santino, who is often tagged by fans as Cheeto Santino. Its exact original recording is not widely documented, so it lives mainly through soundboards, edits and shares rather than one famous scene. That portability helped it spread as a quick audio shorthand for surprise. Because the single word is clear and the tone needs no context, creators reuse it across memes, streams and short videos whenever something earns an instant impressed response.
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A short clip of Andrew Santino saying wow in a drawn out, impressed tone, used as a reaction sound for surprising, funny or unbelievable moments online.
This is a very brief clip of comedian Andrew Santino delivering a single drawn out wow with genuine surprise in his voice. The delivery rises and stretches just enough to feel both impressed and a little stunned, which makes the reaction instantly readable even without any picture. At under a second it lands like a quick punctuation mark in a conversation or edit. Viewers hear it as an honest response to something unexpected, impressive or slightly ridiculous, and that mix of amazement and disbelief is why it works so well as a standalone reaction.