Place it at the peak of a reaction edit, after a short setup clip and before the payoff shot, so the audience is already watching for a response. Follow it with Goofy Ahh Sounds as the next beat, or open with Scream Meme as the first beat in the same sequence.
About this sound
This clip runs just over seven seconds and pairs a long, drawn-out human scream with a string of quick, high-pitched mew sounds. The scream lands loud and over the top, then the mews turn it silly instead of scary, giving the whole thing a startled, cartoonish energy that works best as an exaggerated reaction to something sudden, absurd or painfully loud.