The line comes from the start of Grand Theft Auto: San Andreas, released in 2004, where protagonist Carl Johnson, known as CJ, returns home to Los Santos. Often shared online as Aw Shit Here We Go Again, the moment became a reaction meme in the late 2010s on YouTube and social media. Players and creators reused the clip whenever a game, trend, or problem returned, and its tired tone helped it stay popular far beyond GTA fans as a shorthand for unwanted repetition.
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CJ saying ah shit here we go again from GTA San Andreas, a short voice line used as a meme when the same annoying situation repeats all over again.
This is CJ from Grand Theft Auto: San Andreas delivering his famous opening line after returning to Los Santos, resigned and annoyed that trouble is starting again. His flat, tired delivery makes the moment instantly relatable, because he is not surprised, just fed up. The clip captures that exact feeling of walking straight back into a mess you just escaped. Creators cut it in at the start of a repeat failure, a respawn, or a bad decision, letting CJ speak for everyone watching before the chaos unfolds again in the video.