Put Damn Meme before it as the setup, then follow it with Oh My God Wow for a second reaction or Eww Brother Eww to repeat the judgement. Keep it near the end of a short reaction sequence.
About this sound
This three-second Portuguese voice clip delivers the line 'handsome, but he's fat — ew' in a blunt, judgmental tone, as if reacting to a photo or profile in real time. It feels funny, awkward and a little cruel, because the compliment collapses straight into disgust. The short delivery makes the judgement land harder, turning a casual remark into a sharp reaction.