Place it in the middle of a reaction sequence after the setup line, then follow it with the Auughhh meme sound for an exasperated payoff, or end the sequence there if the next scene already has dialogue waiting.
About this sound
This 6.5-second clip pairs a hyperactive guy with a granny in a brief Chinese sound effect exchange. It feels frantic and funny, like two very different energies colliding in a few seconds, which makes the back-and-forth feel rushed, silly and hard to ignore.