Put it at the very start of an edit to set up a recurring problem, then cut straight to the chaos that follows. Follow it with the Danger Alarm Meme Sound when the situation escalates into full disaster.
About this sound
This is a short voice clip of Carl “CJ” Johnson saying “Ah shit, here we go again” in a calm, flat delivery that lasts just over three seconds. It feels resigned and wearily funny, like bracing for trouble you already know is coming. The line is spoken by CJ at the start of Grand Theft Auto: San Andreas.