Put this clip at the turning point of an edit, after a short reaction beat establishes the mistake. Pair it by preceding it with it was at this moment he knew, then follow it with the Darth Vader Nooo reaction to extend the fallout before returning to normal footage.
About this sound
This is a four-second spoken clip of a voice delivering the line 'Now I am become Death, the destroyer of worlds' in a grave, measured tone. It feels ominous and heavy rather than funny, landing like a final warning after something irreversible has happened, which is why the weight of the words does all the work.