Place it as the final beat of a short edit, right after the other person makes their biggest claim. Open with the shocked meme sound effect to sell the drama, then let this line close the scene, and finish with the oh no no no laugh to turn the dismissal into a shared joke.
About this sound
Gilbert Gottfried delivers the line 'I don't give a shit' in his sharp, nasal voice in a clip lasting just over two seconds. The delivery is harsh, exaggerated and instantly readable, turning total indifference into something funny rather than hostile. It circulates online as a clipped reaction quote, used to shut down drama with one brutally simple answer.