Put it right after the boast or proud introduction in your edit, then follow it with Bruh for the reaction and Emotional Damage to close the joke. Keep Marcello as the centrepiece and let the other clips answer him, rather than stacking several reactions at once.
About this sound
This is an 11-second Italian voice clip in which a man introduces himself as Marcello and then delivers a crude, explicit line about himself. The bluntness makes it shocking and awkwardly funny, the kind of line that lands because it is said so plainly.