Place it as the reaction beat right after a helpful action on screen, then follow it with a softer moment. Pair it with the Mayuri Tuturu Sound Button for a second cute anime reply, or contrast it with the Anime Ahh Sound Button when the gratitude turns to surprise.
About this sound
This is a short 1.6-second voice clip of a cheerful character saying "Thank you very much" in an exaggeratedly polite anime style. It feels warm, grateful, and a little over-the-top, which makes the thanks sound both sincere and funny. The line is from Season 3, Episode 7 of Konosuba.