Place it at the end of a rambling clip, just before the reaction shot, then follow it with a Duck Quack Sound Effect to underline the joke and an Oh No No No Laugh to let the room respond. Keep the sequence tight so the shut-up stays the punchline.
About this sound
This is a very short Dutch spoken clip saying “kwek kwek hou je bek,” roughly a jokey quack quack, shut your mouth, delivered in a sharp, teasing voice. It lands as silly, petty and unexpectedly direct rather than harsh, so the interruption feels playful instead of aggressive. At about a second long, it hits fast and leaves space for the reaction that follows.