Mario has been one of the most recognisable video-game characters for decades, which is why short Mario-style sounds travel so easily across soundboards and short-form video. This clip is shared mainly as a quick gaming reaction, rather than as a full piece of music or dialogue, and creators reuse it whenever a playthrough, challenge or edited fail needs an instant game-over cue. Its staying power comes from that familiarity: viewers do not need context to understand that something has just gone wrong, so the joke works in a few seconds.