My Waifu circulates online as a short fan sound rather than a widely documented clip from a single show, which is part of why it works so well as a meme. Anime fans and meme creators have picked it up for edits, reaction videos and short-form posts where a favourite character is the joke, and its brevity makes it easy to drop into almost any moment. Because the humour comes from the affectionate exaggeration itself rather than a specific plot point, it stays reusable across different characters, fandoms and formats.