Place it in the middle of a repetitive gag, after a setup line, then follow it with a Bruh for the deadpan reaction, or open with Goofy Ahh Sounds to set the tone before it takes over.
About this sound
This 19-second clip repeats a playful nio nio nio vocal chant over and over, turning a simple nonsense syllable into a running gag that gets sillier the longer it goes on. It feels light, goofy and deliberately annoying in the best way, like someone teasing a friend who will not stop talking.