Place it as the punchline right after the offer of another drink, then follow it with Bruh Meme for the group's reaction and Fail Sound Meme if the offer comes again anyway.
About this sound
This is a very short Spanish line in which Enrique Pinti declares, in a firm and fed-up voice, that he will not drink any more. It lands as a comic, stubborn refusal, perfect for shutting down pressure with a laugh rather than an argument. The line comes from the Argentine film Esperando la carroza, where Pinti plays a character pushed to his limit.