Place it near the end of an edit, just after the moment everyone turns on the main character, then follow it with Oh My God Bro Oh Hell Nah for the disbelief and Emotional Damage for the aftermath. If you want a second reaction instead, use Scream Meme after the first one.
About this sound
This is a roughly 15-second spoken clip built around the panicked line 'oh god they tryna drown me,' delivered in a frantic, overwhelmed voice as if someone is being pulled under by a crowd. It feels chaotic, desperate and darkly funny, the kind of over-the-top distress that makes a small mishap sound like a full emergency.