Onii-chan is a Japanese honorific meaning big brother, turned into a running trope by anime and otaku culture, while Vsauce is the YouTube science channel hosted by Michael Stevens that became a meme template for mock-serious explainers in the early 2010s. This clip appears to be a user-made meme mashup stitching the two references together rather than an official release, and that homemade collision is exactly why editors pass it around. It thrives in short-form edits where recognising both halves instantly sells the joke.