The Big Bang Theory ran on CBS from 2007 to 2019 and became one of the most quoted sitcoms online. Bernadette Rostenkowski, played by Melissa Rauch and introduced in season three, was known for her sweet voice and unexpectedly sharp lines. Short clips of her dialogue circulate widely as reaction sounds on soundboards and in edited videos. This polite thank you survives because it needs no context, expresses clear gratitude in about a second, and is instantly tied to the character for fans of the show.