Place it at the reveal in a meme edit, then follow with the You What SpongeBob Sound for a second reaction before the SpongeBob My Leg Sound closes the scene with a familiar callback.
About this sound
This 2.5-second clip catches Patrick Star shouting “Who are you people?!” in a loud, bewildered voice that rises into near-panic. It feels instantly funny because the confusion is so total and so overplayed, turning an ordinary surprise into a cartoonish meltdown. The line comes from SpongeBob SquarePants, where Patrick delivers it as a startled reaction to people he does not recognise.