Place it as the closing reply after the setup clip finishes, then follow with the Sua Mãe Sabe Sound for a second teasing jab, or swap in Tu É Um Beta when the target is the guy being defended rather than his defender.
About this sound
This is a 3.5-second Brazilian Portuguese voice clip of a speaker delivering the line “dá o cu pra ele então,” roughly “then give him your ass.” The delivery is blunt and flat, which makes the line feel crude, sarcastic and dismissively funny rather than serious, landing as an abrupt punchline that cuts off whoever was just talking.