Place it as the final reaction beat after a fail builds, not under dialogue. Lead in with the bruh soundboard button as the setup, then swap to the emotional damage sound button if the reaction needs a second, bigger tag before cutting away.
About this sound
The clip is a short spoken Chinese exclamation, the phrase Gan Ni Niang Lie delivered as a blunt swear in just over two seconds. It lands as rude, confrontational and darkly funny, the kind of outburst that turns a mild annoyance into an exaggerated insult for comic shock value among friends who get the joke.