Put it near the end of a reaction edit, after the setup has landed, then follow it with a baby laughing meme for a second reaction, or switch to a cat laugh meme when the joke turns sillier.
About this sound
This 23-second clip is a repeated 'nhe nhe nhe' vocal laugh, delivered in short bursts that build into a longer playful run. It feels mischievous and knowing, like someone holding back a bigger laugh while enjoying a private joke. The sound works as a light reaction to something cheeky or smug.