Put it in the middle of a food gag, after the setup shows an empty plate and before the reaction shot. Follow it with a Vine Boom for the failed meal, or pair it with a Classic Fart for a longer bodily-humour sequence that ends on the hungry character.
About this sound
This four-second clip turns a hungry stomach rumble into a low, whale-like moan, with a hollow growl that swells, wobbles and fades like a tiny creature calling from an empty belly. It feels silly and oddly sad at once, making hunger obvious without a word. It comes from Sound Ideas, the long-running sound effects library behind many cartoons and games.