The phrase is Dutch, with nog een keer meaning one more time and kanker used here as a strong profanity rather than a medical reference. No verified original recording, speaker or year is documented for this soundboard version, which circulates as a short standalone reaction clip. It spread through meme pages, chat groups and gaming communities where Dutch swearing is often reused for comic frustration. Its brevity and clear emotional tone keep it popular for moments when a mistake, death or setback happens yet again.